What is SPICE?
Originally SPICE was a project funded by the European Union. The main goal of this project was to develop a counterpart to CMMI, especially focused on Small and Medium Enterprises.
SPICE is an abbreviation and stands for "Software Process Improvement and Capability dEtermination". Even if software development was the main driver of the initiative at that time, the "S" in SPICE is nowadays used for the entire system development.
The project was very successful and finally, ISO issued the standard series ISO 15504-x to support the future development of specific standards for all kinds of domains.
In the meantime, most parts of this standard have been replaced by the ISO 330xx series, and we have a choice from various Process Assessment Models. The focus of SPICE has widened to all Software-based Systems and to Operation and Maintenance processes.